Introduction

Welcome to the Genomics Facility at the University of Sheffield! We are a state-of-the-art core facility dedicated to empowering researchers with cutting-edge tools and expertise in genomics. Whether you’re delving into the mysteries of gene expression, navigating the complexities of whole genomes, or exploring the exciting world of single-cell analysis, our facility provides the resources and support to propel your research forward.

The equipment to perform sequencing and other experiments is spread across the University of Sheffield campus. However, by providing these web pages we intend to give you access to the information you need to plan your experiments. Please contact our centralised team and we will discuss the optimal solution to fulfilling your experimental goals.

Testimonials

“A one-stop shop for all your molecular needs! The genomics facility is extremely well equipped and the in-house team has a wealth of experience meaning they can offer expert advice on all aspects from experimental design to bioinformatic analysis. The facility is an integral part of my research, and has helped me get the most out of our budget and data.”

• Dr Luke Dunning - School of Biosciences

The genomics laboratory has been instrumental in assisting my group in adopting and utilizing various genotyping platforms. They have provided comprehensive training, helped with managing plate runs, and actively assisted in data retrieval, analysis, and interpretation. Thanks to their expertise, this technique has become an integral part of our laboratory’s routine for genotyping zebrafish CRISPR mutant lines. I am truly grateful to the genomics laboratory for the continuous technical support at such a high level.

• Dr Heba Ismal – Department of Infection, Immunity and Cardiovascular Disease

Having an in-house genomics laboratory equipped with Oxford Nanopore technology has been immensely beneficial for my PhD. The flexibility and transparency demonstrated by the lab have been invaluable, as they have provided me with real-time updates on sequencing runs. Moreover, they have gone above and beyond to offer demonstrations upon request. Their support and insights have played a vital role in generating high-quality DNA methylation sequencing data from my Arabidopsis plants.

• Adam Parker – School of Biosciences

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The University of Sheffield has other facilities for high-throughput biology that may complement your Genomics experiment and provide other angles of investigation